Eleanor Roosevelt was an American political figure, diplomat and activist. She served as the First Lady of the United States from March 4, 1933, to April 12, 1945, during her husband President Franklin D. Roosevelt's four terms in office, making her the longest-serving First Lady of the United States.
Met in 1902, she would be approximately 18 years old upon meeting the Riddles.
The second time the Riddles meet her is when she is living in the White House as First Lady, so sometime between March 1933 and April 1945. She also mentions hosting her own radio show, which began 9 July 1934, putting her somewhere between 49 and 60 years old.
She was born Anna Eleanor Roosevelt, but more commonly went by her middle name. She did not change her surname when she married Franklin Roosevelt in 1905 (at ~21 years old) because he had the same last name as her: they were fifth cousins once removed.
Eleanor is the only character in the show with visible teeth. This is likely because she is known for having large teeth and an overbite in her earlier days.
She actually made reference to her family's large teeth in a 16 August 1946 account:
I had to spend three and a half hours at the dentist's this morning. A great many years ago, on the steps of the station in Utica, when I was on my way to make a speech one wintry day, I fell and cracked both my front teeth, chipping bits off of them. As a result, I suppose, they were fragile, and so, in this accident, they broke off about halfway up. Now I shall have two lovely porcelain ones, which will look far better than the rather protruding large teeth which most of the Roosevelts have.